Beilstein J. Nanotechnol.2015,6, 167–176, doi:10.3762/bjnano.6.16
experiments should be carried out with different cell lines and other well-defined nanoparticle species to elucidate possible general principles.
Keywords: Caveolin-1; CDC42; endocytosisinhibition; iron oxide nanoparticles; nanoparticle uptake; Introduction
Nanotechnology is expected to be a very powerful
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Figure 1:
Overview of well-known endocytotic pathways and the involved key proteins, target proteins inhibite...
Beilstein J. Nanotechnol.2014,5, 1625–1636, doi:10.3762/bjnano.5.174
; endocytosis; inhibition; nanoparticles; uptake proteins; Introduction
In recent years, the use of engineered nanoparticles (NPs) (defined as <100 nm in three dimensions according to ISO TS 27687:2008) has witnessed a strong rise in biomedical and pharmaceutical applications, specifically for targeted drug
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Figure 1:
Characterization of polystyrene particles. (A) Characteristics of the particles as measured by dyna...